Limbic Activation During Cue-Induced Cocaine Craving

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Limbic activation during cue-induced cocaine craving.

OBJECTIVE Since signals for cocaine induce limbic brain activation in animals and cocaine craving in humans, the objective of this study was to test whether limbic activation occurs during cue-induced craving in humans. METHOD Using positron emission tomography, the researchers measured relative regional cerebral blood flow (CBF) in limbic and comparison brain regions of 14 detoxified male co...

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Activation of memory circuits during cue-elicited cocaine craving.

Evidence accumulated over more than 45 years has indicated that environmental stimuli can induce craving for drugs of abuse in individuals who have addictive disorders. However, the brain mechanisms that subserve such craving have not been elucidated. Here a positron emission tomographic study shows increased glucose metabolism in cortical and limbic regions implicated in several forms of memor...

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Brain Activity During Cue-Induced Craving

In these extraordinary images, Dr. Katherine Bonson and her colleagues at NIDA’s Intramural Research Program have captured the process of a cocaine-related cue triggering craving for cocaine in the brain of an addicted individual. The investigators used positron emission tomography (PET) to create images of brain activity in 11 cocaine-addicted volunteers who reported on the intensity of their ...

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Cannabis cue-induced brain activation correlates with drug craving in limbic and visual salience regions: preliminary results.

Craving is a major motivator underlying drug use and relapse but the neural correlates of cannabis craving are not well understood. This study sought to determine whether visual cannabis cues increase cannabis craving and whether cue-induced craving is associated with regional brain activation in cannabis-dependent individuals. Cannabis craving was assessed in 16 cannabis-dependent adult volunt...

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Counterconditioning reduces cue-induced craving and actual cue-elicited consumption.

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ژورنال

عنوان ژورنال: American Journal of Psychiatry

سال: 1999

ISSN: 0002-953X,1535-7228

DOI: 10.1176/ajp.156.1.11